On January 3, 2019, the Chang'e 4 probe sent back photos of the Von Karman crater in the South Pole-Aitken basin, after its successful soft landing, the first ever by a man-made vehicle, on the surface of the far side of the moon. This feat was hailed as opening a new chapter in mankind's lunar exploration.

Joining hands with their collaborators, CAS researchers have made important contributions to the lunar exploration mission. For instance, the research and development of its ground application system was led by the National Astronomical Observatories, Chinese Academy of Sciences (NAOC), which was in charge of deliberating and presenting the system's science objectives, making scientific exploration plans of the payloads aboard the Chang'e 4,monitoring the payloads' operation, receiving, processing and explaining scientific exploration data, managing and releasing the data, and their applied research.

In addition, the payloads carried by the lunar probe were mainly developed by CAS researchers. For instance,the lunar penetrating radar (LPR) and the very low frequency radio spectrometer (VLFRS) were designed by the CAS Aerospace Information Research Institute (AIR).Both of them began their operations successfully after the soft-landing of the lunar probe, making China the first country conducting radio observation on the far side of the moon and filling the scientific gap of radio astronomical observations at the frequencies between 100KHz～10MHz.

Dark No More: One of the pictures sent back by Chang'e 4, a lunar probe of China, shows a view of the lunar surface from its landing site, the Von Karman crater in the South Pole-Aitken basin of the far side of the moon. Shot by cameras carried by the probe's lander, the pictures mark the first images taken from the far side of the moon. Chang'e 4 started its journey to the moon on Dec 8. (Credit: CLEP/CNSA)

Furthermore, the orbit measurement of the lunar probe was conducted by research teams headed by the CAS Shanghai Astronomical Observatory using very long baseline interferometry (VLBI). The VLBI orbit determination system is composed of different CAS telescopes located in various places, including the Tianma 65m Radio Telescope in Shanghai, the Miyun 50m Radio Telescope in Beijing, the Nanshan 25m Radio Telescope in Xinjiang, and Kunming radio telescope in Yunnan.

留城！这是女友给我下的最后通牒，在短短的两个字背后，女友娇美的笑容背后暗藏的冷漠让我刚刚勃起的躁动，如一堆火苗突然被泼下了一盆冷水，只剩下了一缕被被青烟袅袅而起。彼时我们在校园后山的树林一角约会，当我把这个消息当作喜讯告诉女友，女友却一把打掉我的手。我的手像蛇一样正准备钻入她胸前。

Last but not the least, more than 20 kinds of key materials developed by CAS researchers were employed for the carrier rocket, the inspector and lander of the lunar prober.

2.2 观察组与对照组患儿不同时段NBNA相关指标评分比较 经过不同方式的治疗，观察组患儿治疗后1、2及4周行为能力、被动肌张力等各项NBNA评分均显著高于对照组，不同时段总平均分分别为(36.6±2.5)分、(37.9±2.5)分及(39.5±1.4)分，与对照组比较差异有统计学意义(P<0.05)，见表2。